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Inflammation & Immune Activation

HIV Triggers CD4 T-Cell Death via Inflammation

HIV infection sets off a vicious cycle of inflammation and cell death dubbed "pyroptosis" -- or fiery cell suicide -- according to a pair of recent reports from researchers at UCSF's Gladstone Institutes.

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Changes in Gut Bacteria May Promote Inflammation and HIV Disease Progression

Changes in intestinal bacteria may contribute to disease progression and development of non-AIDS conditions in people with HIV, even those on effective antiretroviral therapy (ART), according to a report in the July 10, 2013, issue of Science Translational Medicine.

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IAS 2013: Management of Age-Related Conditions Is the Future of HIV Care

Other diseases are becoming far more important than AIDS for people with HIV who have consistent access and good response to antiretroviral treatment, and management of age-related comorbidities will become an increasingly important aspect of HIV medicine worldwide in the coming years, Steven Deeks argued in his keynote address yesterday at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013).alt

 

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IAS 2013: Conference Opens with Focus on Aging, Global Guidelines, Drug Users

The 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) kicked off Sunday in Kuala Lumpur, Malaysia. Highlights of the first day included the release of new World Health Organization (WHO) antiretroviral therapy guidelines, a high-level panel on drug policy and public health, and a keynote address on HIV and aging.

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IAS 2013: HIV as a Chronic Disease [VIDEO]

HIV has become a chronic disease for people who have access and respond to antiretroviral therapy, but it leads to persistent immune activation and inflammation that could cause problems as people with HIV reach their 60s, 70s, and 80s, Steven Deeks from the University of California at San Francisco explained at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) in Kuala Lumpur.

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