Inflammation
Inflammation & Immune Activation
EACS 2011: Does Maraviroc Intensification Promote Better CD4 Cell Recovery?
- Details
- Category: HIV Treatment
- Published on Tuesday, 25 October 2011 00:00
- Written by Liz Highleyman
Adding maraviroc (Selzentry or Celsentri) to a suppressive antiretroviral regimen may help promote CD4 T-cell recovery in a subset of patients who experience poor immunological response to treatment, according to 2 studies presented at the 13th European AIDS Conference (EACS 2011) this month in Belgrade.
Does CD8 Cell Activation Affect CD4 Cell Recovery on ART?
- Details
- Category: HIV Basic Science
- Published on Tuesday, 06 September 2011 00:00
- Written by Liz Highleyman
Greater activation of CD8 "killer" T-cells was associated with smaller gains in CD4 "helper" T-cells among people in Uganda who achieved good HIV viral load suppression on antiretroviral therapy (ART), researchers reported in the August 30, 2011, advance online edition of AIDS.
TBR-652 Inhibits HIV, May Dampen Inflammation
- Details
- Category: Experimental HIV Drugs
- Published on Tuesday, 31 May 2011 03:31
- Written by Liz Highleyman
TBR-652, a drug that blocks both CCR5 and CCR2 cell receptors, showed potent antiviral activity against HIV, but did not change most inflammation biomarkers.
Do Statins Reduce Risk of Death for People with HIV?
- Details
- Category: Inflammation & Immune Activation
- Published on Tuesday, 09 August 2011 00:00
- Written by Liz Highleyman
HIV positive people on suppressive antiretroviral therapy (ART) were significantly less likely to die if they were also taking a statin drug to manage blood lipids, researchers reported in the July 12, 2011, online edition of the open access journal PLoS ONE. The researchers suggested that statins' ability to reduce inflammation may have a survival benefit for people with HIV.
Untreated HIV Increases Inflammation in Women
- Details
- Category: Inflammation & Immune Activation
- Published on Tuesday, 24 May 2011 03:42
- Written by Liz Highleyman
Women with untreated HIV infection had different cytokine patterns and higher levels of inflammatory biomarkers than HIV negative WIHS participants, but antiretroviral therapy largely reversed this effect.
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