Preventive Antibiotics for Tuberculosis Lower Risk of Death for People with HIV

Increased screening for tuberculosis (TB) and prophylactic treatment with isoniazid significantly reduced the incidence of active TB disease as well as mortality among patients treated at HIV clinics in Brazil, according to a study published in the August 14, 2013, advance edition of Lancet Infectious Diseases. This is the first evidence that a community-wide effort can prevent people coinfected with HIV and TB from developing active TB disease.


HIV i-Base and TAG Release 2013 Pipeline Report on HIV, Hepatitis C, and TB Therapies

HIV i-Base and the Treatment Action Group (TAG) released their 2013 Pipeline Report this week in conjunction with the International AIDS Society conference (IAS 2013) in Kuala Lumpur. The guide provides the latest status of drugs, diagnostics, and candidate vaccines for HIV, hepatitis C, and tuberculosis.



Vitamin C Rapidly Kills Drug-resistant Tuberculosis Bacteria

Vitamin C causes a chemical reaction that rapidly destroys Mycobacterium tuberculosis that is resistant to isoniazid and other drugs, researchers determined in a serendipitous discovery described in the May 21, 2013, edition of Nature Communications.


Directly Observed Therapy for Tuberculosis No Better than Self-Administration

People who self-administered drugs to treat tuberculosis (TB) and those receiving directly observed therapy (DOT) had similar outcomes, according to a meta-analysis of 10 studies described in the July 2013 issue of Clinical Infectious Diseases


World TB Day: U.S. Cases Hit New Low, Integration with HIV Care Needed Worldwide

The number of new tuberculosis (TB) cases in the U.S. fell below 10,000 in 2012 -- the lowest rate since tallying began in the early 1950s, according to a Centers for Disease Control and Prevention(CDC) report released ahead of World TB Day on March 24. But the news is not all good, as novel treatments and better integration of care are needed on a global basis.