Treatment as Prevention
5. HIV Treatment as Prevention: No Infections in PARTNER Study
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- Category: Treatment as Prevention
- Published on Monday, 12 January 2015 00:00
- Written by HIVandHepatitis.com
Pre-exposure prophylaxis (PrEP) for HIV negative people was the biggest topic in HIV prevention in 2014, but use of antiretroviral therapy by HIV positive people to prevent onward transmission of the virus -- dubbed treatment as prevention or TasP -- also received further support.
San Francisco HIV Forum Asks: Is Undetectable the New Negative?
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- Category: Treatment as Prevention
- Published on Friday, 23 May 2014 00:00
- Written by Liz Highleyman
More than 100 participants packed the Eureka Valley Recreation Center in San Francisco on May 20 for the latest Real Talk discussion of new HIV prevention strategies including pre-exposure prophylaxis (PrEP) and antiretroviral treatment as prevention.
CROI 2014: HIV Treatment as Prevention Works in PARTNER Study
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- Category: Treatment as Prevention
- Published on Wednesday, 05 March 2014 00:00
- Written by HIVandHepatitis.com
No cases of linked HIV transmission were seen during 44,500 condomless sex acts by more than 750 heterosexual and gay couples, according to findings from the PARTNER study presented this week at the Conference on Retroviruses and Opportunistic Infections (CROI 2014).
Treatment as Prevention Dramatically Lowers HIV Sexual Transmission [Press conference video]
No One with Undetectable Viral Load Transmits HIV in PARTNER Study [Study summary]
HIV Transmission through Condomless Sex [Interview with Jens Lundgren]
3/5/14
CROI 2014: HIV Transmission through Condomless Sex [VIDEO]
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- Category: Treatment as Prevention
- Published on Wednesday, 05 March 2014 00:00
- Written by Gregory Fowler
An analysis of more than 750 serodiscordant heterosexual and gay couples in the PARTER study who engaged in more than 45,000 condomless sex acts found no cases of linked HIV transmission when the positive partner was on effective antiretroviral therapy (ART), confirming that treatment as prevention works, according to a report at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston.
CROI 2014: Treatment as Prevention Dramatically Lowers HIV Sexual Transmission [VIDEO]
- Details
- Category: Treatment as Prevention
- Published on Tuesday, 04 March 2014 00:00
- Written by Gregory Fowler
A large study of heterosexual and gay couples saw no cases of linked HIV transmission during 44,500 condomless sex acts when the positive partner was on combination antiretroviral therapy (ART) with suppressed viral load, according to a presentation at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston. Based on these findings, there is no reason for legal action against people not using condoms while on effective ART.
[Jens Lundgrenspeaks at CROI 2014 press conference, Boston, March 4, 2014]
Jens Lundgren from the University of Copenhagen reported the first findings from the PARTNER study, looking at HIV transmission within more than 750 serodiscordant couples -- together contributing nearly 900 years of follow-up -- who reported not using condoms.
While this much condomless vaginal and anal sex would be expected to lead to 50 to 100 transmissions, based on historical data, the researchers did not see any cases of linked transmission in which newly acquired HIV matched a partner's strain.
While the risk of transmission per sex act while on ART fell to nearly zero, the cumulative risk over time must still be considered. Lundgren said. Estimates of risk over 10 years may reach as high as 1 in 25 overall, or up to 1 in 10 for anal sex. Whether this level of risk is acceptable "is not for us to say, but for people to decide," he said.
Lundgren emphasized, however, that there is "no reasonable legal action you can take against people for not using condoms" if they are on effective ART, and no indication for post-exposure prophylaxis (PEP) in this situation.
These findings support the recent decision by the Centers for Disease Control and Prevention (CDC) -- at the urging of activists -- to refer to "condomless sex" rather than "unprotected sex," recognizing that there are other effective prevention approaches besides condom use.
See also:
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CROI 2014: No One with Undetectable Viral Load Transmits HIV in PARTNER Study [STUDY SUMMARY]
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CROI 2014: HIV Transmission through Condomless Sex -- Interview with Jens Lundgren [VIDEO]
3/5/14
Sources
A Rodger, T Bruun, V Cambiano, J Lundgren, et al. HIV Transmission Risk Through Condomless Sex If HIV+ Partner On Suppressive ART: PARTNER Study. Conference on Retroviruses and Opportunistic Infections (CROI 2014). Boston, March 3-6. Abstract 153LB.
Press conference. 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014). Boston. March 4, 2014.
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- CROI 2014: No One with Undetectable Viral Load Transmits HIV in PARTNER Study
- PopART Study Will Look at HIV Treatment as Prevention on a Population Level
- IAS 2013: No Increase in Risk Behavior among People Taking ART, Meta-Analysis Shows
- ICAAC 2012: HIV May Be Shed in Semen Even If Blood Viral Load Is Undetectable