HBV Disease Progression
Appetite-regulating Hormone Ghrelin May Inhibit Inflammation and Liver Fibrosis
- Details
- Category: Fibrosis & Cirrhosis
- Published on Tuesday, 23 March 2010 14:02
- Written by Liz Highleyman
Ghrelin, an appetite-regulating hormone produced primarily in the stomach, reduced liver fibrosis, inflammation, and oxidative stress in rats and protected them from both chronic and acute liver injury, according to a study published in the March 2010 issue of Hepatology. Researchers also found that ghrelin levels were lower in chronic hepatitis patients with advanced fibrosis. If confirmed in future studies, ghrelin may have potential as an anti-fibrotic therapy.
Bone Loss and Vitamin D Deficiency Are Common among People with Liver Cirrhosis
- Details
- Category: Fibrosis & Cirrhosis
- Published on Tuesday, 01 September 2009 14:01
- Written by Liz Highleyman
People with liver cirrhosis -- a potential outcome of chronic hepatitis B or C -- frequently experience bone loss, or reduced bone mineral density (BMD), and often have low vitamin D levels, according to an Indian study published in the July 28, 2009 issue of World Journal of Gastroenterology.
Two Studies Look at Promising Therapies for Liver Cancer: Sorafenib and Doxorubicin
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- Category: Liver Cancer/HCC
- Published on Friday, 25 July 2008 00:00
- Written by Liz Highleyman
Two recently published studies produced promising data on experimental therapies for HCC: the systemic chemotherapy drug sorafenib (Nexavar), and combination therapy using doxorubicin-eluting beads plus radiofrequency ablation.
EASL 2009: Does HBV Viral Load Level Predict Development of Liver Fibrosis?
- Details
- Category: HBV Disease Progression
- Published on Friday, 29 May 2009 13:47
- Written by Liz Highleyman
Two studies presented at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL 2009) last month in Copenhagen looked at the association between HBV DNA level and development of fibrosis, with findings suggesting that the role of HBV viral load differs for hepatitis B "e" antigen (HBeAg) negative and HBeAg positive individuals.
Association between Hepatitis B and C Virus Infection and Extrahepatic Bile Duct Cancer
- Details
- Category: HBV Disease Progression
- Published on Friday, 13 June 2008 14:01
- Written by Liz Highleyman
It is well known that chronic infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to advanced liver disease, including hepatocellular carcinoma (a form of primary liver cancer) over the course of years or decades. Now, a new study published in the April 15, 2008 International Journal of Cancer indicates that viral hepatitis may also promote development of cancer of the extrahepatic bile duct, which transports bile from the liver to the small intestine, joining with a similar duct from the gall bladder.
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